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Patrick Bruneval Selected Research

benfluorex (S 780)

1/2018Benfluorex-induced severe primary tricuspid and mitral regurgitation requiring a double-valve replacement.
1/2017Fatal postoperative systemic pulmonary hypertension in benfluorex-induced valvular heart disease surgery: A case report.
12/2015Sub-aortic obstruction of left ventricular outflow tract secondary to benfluorex-induced endocardial fibrosis.
4/2015Fatal dynamic mitral regurgitation as a presentation of benfluorex-Induced valvular heart toxicity.
2/2015Benfluorex: An active toxin for the development of aortic valve stenosis.
1/2015Calcifications in benfluorex-induced valve heart disease: a misknown association.
1/2015Operative finding of aortic cusp prolapse in benfluorex-induced aortic regurgitation.
12/2014Benfluorex-induced mitral stenosis: a misknown etiology.
3/2012[Letter on the article: "benfluorex and valvular heart disease"].

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Patrick Bruneval Research Topics

Disease

18Neoplasms (Cancer)
12/2019 - 05/2002
16Fibrosis (Cirrhosis)
06/2022 - 09/2002
16Myocardial Infarction
01/2021 - 07/2002
15Inflammation (Inflammations)
01/2022 - 11/2002
14Hypertension (High Blood Pressure)
08/2015 - 07/2002
10Cicatrix (Scar)
10/2008 - 09/2002
8Pathologic Constriction (Stenosis)
06/2022 - 07/2010
8Thrombosis (Thrombus)
11/2020 - 03/2004
8Atherosclerosis
01/2018 - 03/2008
7Heart Failure
09/2015 - 06/2003
6Dilated Cardiomyopathy (Cardiomyopathy, Congestive)
01/2019 - 07/2002
6Ischemia
01/2016 - 07/2002
5Heart Valve Diseases (Valvular Heart Disease)
06/2022 - 03/2012
5Cardiomyopathies (Cardiomyopathy)
02/2021 - 04/2003
5Heart Arrest (Cardiac Arrest)
02/2020 - 12/2013
5Infections
01/2019 - 09/2005
5Infarction (Infarctions)
10/2018 - 07/2002
4Hypoxia (Hypoxemia)
11/2020 - 07/2005
4Aortic Valve Stenosis (Aortic Stenosis)
10/2020 - 02/2015
4Renal Insufficiency (Renal Failure)
01/2018 - 01/2013
4Focal Segmental Glomerulosclerosis (Glomerulosclerosis, Focal)
10/2014 - 02/2001
4Proteinuria
10/2014 - 03/2007
4Hypertrophy
07/2010 - 07/2002
3Anastomotic Leak
01/2022 - 10/2010
3Ventricular Remodeling
01/2021 - 09/2012
3Myocarditis (Carditis)
09/2020 - 06/2009
3Wounds and Injuries (Trauma)
12/2019 - 01/2018
3Disease Progression
01/2019 - 12/2007
3Papillomavirus Infections
11/2018 - 02/2004
3Mitral Valve Insufficiency (Mitral Regurgitation)
01/2018 - 01/2015
3Head and Neck Neoplasms (Head and Neck Cancer)
01/2018 - 05/2008
3Arteriosclerosis
08/2015 - 01/2008
3Myocardial Ischemia (Ischemic Heart Diseases)
05/2015 - 07/2013
3Albuminuria
08/2009 - 07/2002
3Diabetic Nephropathies (Diabetic Nephropathy)
08/2009 - 09/2003
3Nephrotic Syndrome (Syndrome, Nephrotic)
02/2009 - 02/2001
2Endocarditis
07/2021 - 12/2003
2Acidosis
03/2021 - 10/2008
2Abdominal Aortic Aneurysm
01/2021 - 01/2019
2Vasculitis (Vasculitides)
01/2020 - 05/2011
2Squamous Cell Carcinoma (Epidermoid Carcinoma)
11/2018 - 01/2018
2Shock
01/2018 - 01/2018
2Lung Neoplasms (Lung Cancer)
01/2017 - 07/2010
2Rheumatic Fever (Acute Articular Rheumatism)
01/2017 - 10/2016
2Hypothermia
01/2016 - 04/2014
2Prolapse
12/2015 - 01/2015

Drug/Important Bio-Agent (IBA)

9benfluorex (S 780)IBA
01/2018 - 03/2012
8CollagenIBA
01/2014 - 09/2002
7Biomarkers (Surrogate Marker)IBA
10/2020 - 03/2011
7ReninIBA
08/2015 - 01/2002
6CytokinesIBA
01/2020 - 11/2006
6Biological ProductsIBA
10/2016 - 02/2009
6Proteins (Proteins, Gene)FDA Link
01/2012 - 02/2001
5RNA (Ribonucleic Acid)IBA
10/2022 - 10/2012
5Therapeutic UsesIBA
07/2015 - 10/2002
4AntibodiesIBA
01/2022 - 05/2011
4Peptides (Polypeptides)IBA
12/2016 - 10/2008
4Messenger RNA (mRNA)IBA
09/2015 - 01/2002
4KininsIBA
07/2013 - 05/2009
4SaltsIBA
08/2012 - 07/2002
4VimentinIBA
09/2005 - 02/2001
3Pharmaceutical PreparationsIBA
06/2022 - 10/2016
3Angiotensin IIIBA
01/2021 - 07/2010
3DNA (Deoxyribonucleic Acid)IBA
12/2019 - 12/2003
3FibrinIBA
12/2017 - 03/2015
3salicylhydroxamic acid (SHAM)IBA
09/2015 - 04/2014
3Myosin Heavy Chains (Myosin Heavy Chain)IBA
09/2015 - 09/2002
3GadoliniumIBA
01/2013 - 03/2008
3Tissue Kallikreins (Tissue Kallikrein)IBA
08/2012 - 05/2009
3Matrix Metalloproteinases (MMPs)IBA
03/2008 - 11/2002
3Proliferating Cell Nuclear Antigen (PCNA)IBA
09/2005 - 09/2003
3podocalyxinIBA
09/2005 - 02/2001
3EpitopesIBA
09/2005 - 02/2001
2Triggering Receptor Expressed on Myeloid Cells-1IBA
10/2022 - 01/2021
2ArgonIBA
03/2021 - 01/2018
2Granzymes (Granzyme)IBA
01/2021 - 12/2005
2Immune Checkpoint InhibitorsIBA
09/2020 - 01/2013
2FluorocarbonsIBA
02/2020 - 04/2014
2Adenosine (Adenocard)FDA LinkGeneric
01/2020 - 07/2002
2Intravenous Immunoglobulins (IVIG)FDA Link
01/2020 - 01/2003
2EnzymesIBA
01/2019 - 03/2008
2Transforming Growth Factors (Transforming Growth Factor)IBA
01/2019 - 01/2012
2Interleukin-10 (Interleukin 10)IBA
01/2018 - 09/2015
2CholesterolIBA
01/2018 - 10/2016
2Immunoglobulin G (IgG)IBA
01/2018 - 01/2003
2Indicators and Reagents (Reagents)IBA
03/2016 - 02/2011
2Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
12/2015 - 03/2015

Therapy/Procedure

18Therapeutics
07/2021 - 05/2002
15Injections
10/2018 - 09/2002
11Transplantation
03/2015 - 09/2002
9Stents
01/2022 - 02/2008
9Ligation
08/2011 - 09/2003
6Cell- and Tissue-Based Therapy (Cell Therapy)
01/2014 - 01/2006
5Liquid Ventilation
02/2020 - 12/2013
5Heart Transplantation (Grafting, Heart)
01/2019 - 05/2002
3Catheters
01/2020 - 08/2005
3Immunotherapy
01/2017 - 06/2005
3Kidney Transplantation
10/2014 - 02/2001
3Cell Transplantation
05/2009 - 03/2007
3Cardiomyoplasty
05/2005 - 05/2002